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Rapid population-wide declines in stem cell number and activity during reproductive aging in C. elegans

C. elegans hermaphrodites display dramatic age-related decline of reproduction early in life, while somatic functions are still robust. To understand reproductive aging, we analyzed the assembly line of oocyte production that generates fertilized eggs. Aging germlines displayed both sporadic and pop...

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Bibliografske podrobnosti
izdano v:Development
Main Authors: Kocsisova, Zuzana, Kornfeld, Kerry, Schedl, Tim
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503983/
https://ncbi.nlm.nih.gov/pubmed/30936182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.173195
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