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Rapid population-wide declines in stem cell number and activity during reproductive aging in C. elegans

C. elegans hermaphrodites display dramatic age-related decline of reproduction early in life, while somatic functions are still robust. To understand reproductive aging, we analyzed the assembly line of oocyte production that generates fertilized eggs. Aging germlines displayed both sporadic and pop...

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Podrobná bibliografie
Vydáno v:Development
Hlavní autoři: Kocsisova, Zuzana, Kornfeld, Kerry, Schedl, Tim
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503983/
https://ncbi.nlm.nih.gov/pubmed/30936182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.173195
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