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Rapid population-wide declines in stem cell number and activity during reproductive aging in C. elegans
C. elegans hermaphrodites display dramatic age-related decline of reproduction early in life, while somatic functions are still robust. To understand reproductive aging, we analyzed the assembly line of oocyte production that generates fertilized eggs. Aging germlines displayed both sporadic and pop...
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| Udgivet i: | Development |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6503983/ https://ncbi.nlm.nih.gov/pubmed/30936182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.173195 |
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