Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

Although obesity with associated inflammation is now recognized as a risk factor for breast cancer and distant metastases, the functional basis for these connections remain poorly understood. Here, we show that in breast cancer patients and in animal breast cancer models, obesity is a sufficient cau...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Nagahashi, Masayuki, Yamada, Akimitsu, Katsuta, Eriko, Aoyagi, Tomoyoshi, Huang, Wei-Ching, Terracina, Krista P., Hait, Nitai C., Allegood, Jeremy C., Tsuchida, Junko, Yuza, Kizuki, Nakajima, Masato, Abe, Manabu, Sakimura, Kenji, Milstien, Sheldon, Wakai, Toshifumi, Spiegel, Sarah, Takabe, Kazuaki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945803/
https://ncbi.nlm.nih.gov/pubmed/29351902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1423
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