Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex

BACKGROUND: Cognitive impairment in schizophrenia, aging, and Alzheimer’s disease is associated with spine and synapse loss from the dorsolateral prefrontal cortex (dlPFC) layer III. Complement cascade signaling is critical in driving spine loss and disease pathogenesis. Complement signaling is init...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Datta, Dibyadeep, Leslie, Shannon N., Morozov, Yury M., Duque, Alvaro, Rakic, Pasko, van Dyck, Christopher H., Nairn, Angus C., Arnsten, Amy F. T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945481/
https://ncbi.nlm.nih.gov/pubmed/31906973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1683-1
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi