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Ultrastructural Evidence for Impaired Mitochondrial Fission in the Aged Rhesus Monkey Dorsolateral Prefrontal Cortex

Dorsolateral prefrontal cortex (dlPFC) mediates high-order cognitive functions that are impaired early in the aging process in monkeys and humans. Here, we report pronounced changes in mitochondrial morphology in dendrites of dlPFC neurons from aged rhesus macaques. Electron microscopy paired with 3...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurobiol Aging
Main Authors: Morozov, Yury M., Datta, Dibyadeep, Paspalas, Constantinos D., Arnsten, Amy F.T.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292282/
https://ncbi.nlm.nih.gov/pubmed/28027494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.12.001
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