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Ultrastructural Evidence for Impaired Mitochondrial Fission in the Aged Rhesus Monkey Dorsolateral Prefrontal Cortex

Dorsolateral prefrontal cortex (dlPFC) mediates high-order cognitive functions that are impaired early in the aging process in monkeys and humans. Here, we report pronounced changes in mitochondrial morphology in dendrites of dlPFC neurons from aged rhesus macaques. Electron microscopy paired with 3...

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Detaylı Bibliyografya
Yayımlandı:Neurobiol Aging
Asıl Yazarlar: Morozov, Yury M., Datta, Dibyadeep, Paspalas, Constantinos D., Arnsten, Amy F.T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292282/
https://ncbi.nlm.nih.gov/pubmed/28027494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.12.001
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