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Ultrastructural Evidence for Impaired Mitochondrial Fission in the Aged Rhesus Monkey Dorsolateral Prefrontal Cortex

Dorsolateral prefrontal cortex (dlPFC) mediates high-order cognitive functions that are impaired early in the aging process in monkeys and humans. Here, we report pronounced changes in mitochondrial morphology in dendrites of dlPFC neurons from aged rhesus macaques. Electron microscopy paired with 3...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Morozov, Yury M., Datta, Dibyadeep, Paspalas, Constantinos D., Arnsten, Amy F.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292282/
https://ncbi.nlm.nih.gov/pubmed/28027494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.12.001
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