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In vitro and in silico insights into tyrosinase inhibitors with (E)-benzylidene-1-indanone derivatives

Tyrosinase is a key enzyme responsible for melanin biosynthesis and is effective in protecting skin damage caused by ultraviolet radiation. As part of ongoing efforts to discover potent tyrosinase inhibitors, we systematically designed and synthesized thirteen (E)-benzylidene-1-indanone derivatives...

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Dettagli Bibliografici
Pubblicato in:Comput Struct Biotechnol J
Autori principali: Jung, Hee Jin, Noh, Sang Gyun, Park, Yujin, Kang, Dongwan, Chun, Pusoon, Chung, Hae Young, Moon, Hyung Ryong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944710/
https://ncbi.nlm.nih.gov/pubmed/31921392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.07.017
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