In vitro and in silico insights into tyrosinase inhibitors with (E)-benzylidene-1-indanone derivatives

Tyrosinase is a key enzyme responsible for melanin biosynthesis and is effective in protecting skin damage caused by ultraviolet radiation. As part of ongoing efforts to discover potent tyrosinase inhibitors, we systematically designed and synthesized thirteen (E)-benzylidene-1-indanone derivatives...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Jung, Hee Jin, Noh, Sang Gyun, Park, Yujin, Kang, Dongwan, Chun, Pusoon, Chung, Hae Young, Moon, Hyung Ryong
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944710/
https://ncbi.nlm.nih.gov/pubmed/31921392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.07.017
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