Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico

Tyrosinase is a key enzyme in melanin synthesis, catalyzing the initial rate-limiting steps of melanin synthesis. Abnormal and excessive melanin synthesis is the primary cause of serious skin disorders including melasma, senile lentigo, freckles, and age spots. In attempts to find potent and safe ty...

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Publicado en:Molecules
Main Authors: Bang, EunJin, Noh, Sang-Gyun, Ha, Sugyeong, Jung, Hee Jin, Kim, Dae Hyun, Lee, A Kyoung, Hyun, Min Kyung, Kang, Dongwan, Lee, Sanggwon, Park, Chaeun, Moon, Hyung Ryong, Chung, Hae Young
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321646/
https://ncbi.nlm.nih.gov/pubmed/30551624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123307
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