UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop

Ubiquitin-conjugating enzyme E2O (UBE2O) is a large E2 ubiquitin-conjugating enzyme that possesses both E2 and E3 ligase activities. Ectopic UBE2O overexpression is associated with a variety of human diseases, especially cancers. However, the expression profile and functional biology of UBE2O in hum...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liu, Xu, Ma, Fei, Liu, Chunxiao, Zhu, Kaiyuan, Li, Wenjie, Xu, Yuting, Li, Ge, Niu, Zhenbo, Liu, Jiaxin, Chen, Du, Li, Zhigao, Fu, Yingqiang, Qian, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944706/
https://ncbi.nlm.nih.gov/pubmed/31907353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2194-9
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