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Emissive Synthetic Cofactors: A Highly Responsive NAD(+) Analogue Reveals Biomolecular Recognition Features
Apart from its vital function as a redox cofactor, nicotinamide adenine dinucleotide (NAD(+)) has emerged as a crucial substrate for NAD(+)-consuming enzymes, including poly(ADP-ribosyl)transferase 1 (PARP1) and CD38/CD157. Their association with severe diseases, such as cancer, Alzheimer’s disease,...
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| Опубликовано в: : | Chemistry |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944523/ https://ncbi.nlm.nih.gov/pubmed/30648291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201805520 |
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