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Caught in the act: LRRK2 in exosomes

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are a frequent genetic cause of late-onset Parkinson’s disease (PD) and a target for therapeutic approaches. LRRK2 protein can influence vesicle trafficking events in the cytosol, with action both in endosomal and lysosomal pathways in diffe...

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Sonraí Bibleagrafaíochta
Foilsithe in:Biochem Soc Trans
Main Authors: Wang, Shijie, West, Andrew B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944476/
https://ncbi.nlm.nih.gov/pubmed/30837321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20180467
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