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Exosome markers of LRRK2 kinase inhibition
Hyper-activated LRRK2 is linked to Parkinson’s disease susceptibility and progression. Quantitative measures of LRRK2 inhibition, especially in the brain, maybe critical in the development of successful LRRK2-targeting therapeutics. In this study, two different brain-penetrant and selective LRRK2 sm...
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| Publicado no: | NPJ Parkinsons Dis |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7666125/ https://ncbi.nlm.nih.gov/pubmed/33298972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-020-00138-7 |
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