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Crossover interference and sex-specific genetic maps shape identical by descent sharing in close relatives
Simulations of close relatives and identical by descent (IBD) segments are common in genetic studies, yet most past efforts have utilized sex averaged genetic maps and ignored crossover interference, thus omitting features known to affect the breakpoints of IBD segments. We developed Ped-sim, a meth...
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| 發表在: | PLoS Genet |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944377/ https://ncbi.nlm.nih.gov/pubmed/31860654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007979 |
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