Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection

As genetic datasets increase in size, the fraction of samples with one or more close relatives grows rapidly, resulting in sets of mutually related individuals. We present DRUID—deep relatedness utilizing identity by descent—a method that works by inferring the identical-by-descent (IBD) sharing pro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Hum Genet
Prif Awduron: Ramstetter, Monica D., Shenoy, Sushila A., Dyer, Thomas D., Lehman, Donna M., Curran, Joanne E., Duggirala, Ravindranath, Blangero, John, Mezey, Jason G., Williams, Amy L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035284/
https://ncbi.nlm.nih.gov/pubmed/29937093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.05.008
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