Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection

As genetic datasets increase in size, the fraction of samples with one or more close relatives grows rapidly, resulting in sets of mutually related individuals. We present DRUID—deep relatedness utilizing identity by descent—a method that works by inferring the identical-by-descent (IBD) sharing pro...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Ramstetter, Monica D., Shenoy, Sushila A., Dyer, Thomas D., Lehman, Donna M., Curran, Joanne E., Duggirala, Ravindranath, Blangero, John, Mezey, Jason G., Williams, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035284/
https://ncbi.nlm.nih.gov/pubmed/29937093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.05.008
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