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Computation of identity-by-descent proportions shared by two siblings.
I provide a novel approach to computing the mean and variance of the proportion of genetic material shared identical by descent (IBD) by sibling pairs in a specified chromosomal region, conditional on observed marker data. I first show that each chromosome in an offspring can be represented by a two...
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| Autore principale: | |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1994
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1918183/ https://ncbi.nlm.nih.gov/pubmed/8198133 |
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