Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria

Kinase inhibitors comprise a diverse cohort of chemical scaffolds that are active in multiple biological systems. Currently, thousands of eukaryotic kinase inhibitors are commercially available, have well-characterized targets, and often carry pharmaceutically favorable toxicity profiles. Recently,...

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Udgivet i:ACS Infect Dis
Main Authors: Barker, William T., Nemeth, Ansley M., Brackett, Sara M., Basak, Akash K., Chandler, Courtney E., Jania, Leigh A., Zuercher, William J., Melander, Roberta J., Koller, Beverly H., Ernst, Robert K., Melander, Christian
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944324/
https://ncbi.nlm.nih.gov/pubmed/31434474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00212
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