Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria

Kinase inhibitors comprise a diverse cohort of chemical scaffolds that are active in multiple biological systems. Currently, thousands of eukaryotic kinase inhibitors are commercially available, have well-characterized targets, and often carry pharmaceutically favorable toxicity profiles. Recently,...

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Bibliografiset tiedot
Julkaisussa:ACS Infect Dis
Päätekijät: Barker, William T., Nemeth, Ansley M., Brackett, Sara M., Basak, Akash K., Chandler, Courtney E., Jania, Leigh A., Zuercher, William J., Melander, Roberta J., Koller, Beverly H., Ernst, Robert K., Melander, Christian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944324/
https://ncbi.nlm.nih.gov/pubmed/31434474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00212
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