Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria

Kinase inhibitors comprise a diverse cohort of chemical scaffolds that are active in multiple biological systems. Currently, thousands of eukaryotic kinase inhibitors are commercially available, have well-characterized targets, and often carry pharmaceutically favorable toxicity profiles. Recently,...

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Библиографические подробности
Опубликовано в: :ACS Infect Dis
Главные авторы: Barker, William T., Nemeth, Ansley M., Brackett, Sara M., Basak, Akash K., Chandler, Courtney E., Jania, Leigh A., Zuercher, William J., Melander, Roberta J., Koller, Beverly H., Ernst, Robert K., Melander, Christian
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944324/
https://ncbi.nlm.nih.gov/pubmed/31434474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00212
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