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Effect of Protein Isotope Labeling on the Catalytic Mechanism of Lactate Dehydrogenase
We investigate how isotopic labeling of the enzyme lactate dehydrogenase (LDH) affects its function. LDH is of special interest because there exists a line of residues spanning the protein that are involved in the transition state (TS) of the chemical reaction coordinate (so-called promoting vibrati...
Tallennettuna:
| Julkaisussa: | J Phys Chem B |
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| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944281/ https://ncbi.nlm.nih.gov/pubmed/31644296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b08656 |
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