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On the Pathway of Forming Enzymatically Productive Ligand-Protein Complexes in Lactate Dehydrogenase
We have carried out a series of studies on the binding of a substrate mimic to the enzyme lactate dehydrogenase (LDH) using advanced kinetic approaches, which begin to provide a molecular picture of the dynamics of ligand binding for this protein. Binding proceeds via a binding-competent subpopulati...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440432/ https://ncbi.nlm.nih.gov/pubmed/18390601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.128884 |
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