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Conformational heterogeneity within the Michaelis complex of lactate dehydrogenase

A series of isotope edited IR measurements, both static as well as temperature jump relaxation spectroscopy, are performed on lactate dehydrogenase (LDH) to determine the ensemble of structures available to its Michaelis complex. There clearly has been a substantial reduction in the number of states...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Deng, Hua, Vu, Dung V., Clinch, Keith, Desamero, Ruel, Dyer, R. Brian, Callender, Robert
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111758/
https://ncbi.nlm.nih.gov/pubmed/21568287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp2015929
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