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Resolution of Submillisecond Kinetics of Multiple Reaction Pathways for Lactate Dehydrogenase

Enzymes are known to exhibit conformational flexibility. An important consequence of this flexibility is that the same enzyme reaction can occur via multiple reaction pathways on a reaction landscape. A model enzyme for the study of reaction landscapes is lactate dehydrogenase. We have previously us...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Reddish, Michael J., Callender, Robert, Dyer, R. Brian
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425397/
https://ncbi.nlm.nih.gov/pubmed/28494956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.031
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