The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease

Synaptic dysfunction is an early pathogenic event in Alzheimer disease (AD) that contributes to network disturbances and cognitive decline. Some synapses are more vulnerable than others, including the synapses of the perforant path, which provides the main excitatory input to the hippocampus. To elu...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Haytural, Hazal, Mermelekas, Georgios, Emre, Ceren, Nigam, Saket Milind, Carroll, Steven L., Winblad, Bengt, Bogdanovic, Nenad, Barthet, Gaël, Granholm, Ann-Charlotte, Orre, Lukas M., Tjernberg, Lars O., Frykman, Susanne
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944231/
https://ncbi.nlm.nih.gov/pubmed/31699905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001737
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