The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease

Synaptic dysfunction is an early pathogenic event in Alzheimer disease (AD) that contributes to network disturbances and cognitive decline. Some synapses are more vulnerable than others, including the synapses of the perforant path, which provides the main excitatory input to the hippocampus. To elu...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Haytural, Hazal, Mermelekas, Georgios, Emre, Ceren, Nigam, Saket Milind, Carroll, Steven L., Winblad, Bengt, Bogdanovic, Nenad, Barthet, Gaël, Granholm, Ann-Charlotte, Orre, Lukas M., Tjernberg, Lars O., Frykman, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944231/
https://ncbi.nlm.nih.gov/pubmed/31699905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001737
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