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Rational De Novo Design of a Cu-Metalloenzyme for Superoxide Dismutation
Superoxide dismutases (SODs) are highly efficient enzymes for superoxide dismutation and the first line of defense against oxidative stress. These metalloproteins contain a redox active metal ion in their active site (Mn, Cu, Fe, Ni) with a tightly controlled reduction potential found in a close ran...
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| Publicado en: | Chemistry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944188/ https://ncbi.nlm.nih.gov/pubmed/31710732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201903808 |
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