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De Novo Design and Characterization of Copper Metallopeptides Inspired by Native Cupredoxins

Using de novo protein design, we incorporated a copper metal binding site within the three-helix bundle α(3)D (Walsh et al. Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 5486–5491) to assess whether a cupredoxin center within an α-helical domain could mimic the spectroscopic, structural, and redox feature...

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Publicat a:Inorg Chem
Autors principals: Plegaria, Jefferson S., Duca, Matteo, Tard, Cédric, Friedlander, Thomas J., Deb, Aniruddha, Penner-Hahn, James E., Pecoraro, Vincent L.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241702/
https://ncbi.nlm.nih.gov/pubmed/26381361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.5b01330
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