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Biosynthetic engineering of the antifungal, anti-MRSA auroramycin
Using an established CRISPR-Cas mediated genome editing technique for streptomycetes, we explored the combinatorial biosynthesis potential of the auroramycin biosynthetic gene cluster in Streptomyces roseosporous. Auroramycin is a potent anti-MRSA polyene macrolactam. In addition, auroramycin has an...
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| 出版年: | Microb Cell Fact |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6943886/ https://ncbi.nlm.nih.gov/pubmed/31906943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1274-y |
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