Bromomethylthioindole Inspired Carbazole Hybrids as Promising Class of Anti-MRSA Agents

[Image: see text] Series of N-substituted carbazole analogues bearing an indole ring were synthesized as anti-methicillin-resistant Staphylococcus aureus (MRSA) agents from a molecular hybridization approach. The representative compound 19 showed an MIC = 1 μg/mL against a panel of MRSA clinical iso...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ACS Med Chem Lett
Hauptverfasser: Cheng, Chia-Yi, Chang, Chun-Ping, Lauderdale, Tsai-Ling Yang, Yu, Guann-Yi, Lee, Jinq-Chyi, Jhang, Yi-Wun, Wu, Chien-Huang, Ke, Yi-Yu, Sadani, Amit A., Yeh, Ching-Fang, Huang, I-Wen, Kuo, Yi-Ping, Tsai, De-Jiun, Yeh, Teng-Kuang, Tseng, Chen-Tso, Song, Jen-Shin, Liu, Yu-Wei, Tsou, Lun K., Shia, Kak-Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2016
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5151138/
https://ncbi.nlm.nih.gov/pubmed/27994762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00289
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge