Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin

In this study, we report antifungal activity of auroramycin against Candida albicans, Candida tropicalis, and Cryptococcus neoformans. Auroramycin, a potent antimicrobial doubly glycosylated 24-membered polyene macrolactam, was previously isolated and characterized, following CRISPR-Cas9 mediated ac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wong, Jin Huei, Alfatah, Mohammad, Kong, Kiat Whye, Hoon, Shawn, Yeo, Wan Lin, Ching, Kuan Chieh, Jie Hui Goh, Corinna, Zhang, Mingzi M., Lim, Yee Hwee, Wong, Fong Tian, Arumugam, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557514/
https://ncbi.nlm.nih.gov/pubmed/31181115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218189
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