Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin

In this study, we report antifungal activity of auroramycin against Candida albicans, Candida tropicalis, and Cryptococcus neoformans. Auroramycin, a potent antimicrobial doubly glycosylated 24-membered polyene macrolactam, was previously isolated and characterized, following CRISPR-Cas9 mediated ac...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Wong, Jin Huei, Alfatah, Mohammad, Kong, Kiat Whye, Hoon, Shawn, Yeo, Wan Lin, Ching, Kuan Chieh, Jie Hui Goh, Corinna, Zhang, Mingzi M., Lim, Yee Hwee, Wong, Fong Tian, Arumugam, Prakash
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557514/
https://ncbi.nlm.nih.gov/pubmed/31181115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218189
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