SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer

Dysregulation of the ubiquitin-proteasome pathway is closely associated with cancer initiation and progression. SPOP is an adapter protein of the CUL3-based E3 ubiquitin ligase complexes. Several whole genome/exome sequencing studies on endometrial cancers (ECs) revealed that the SPOP gene is freque...

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Dettagli Bibliografici
Pubblicato in:Am J Cancer Res
Autori principali: Jin, Xiaofeng, Wang, Jian, Li, Qian, Zhuang, Hui, Yang, Jianye, Lin, Zihan, Lin, Ting, Lv, Zeheng, Shen, Liliang, Yan, Chunhong, Zheng, Jingfei, Zhu, Jie, Gong, Zhaohui, Wang, Chenji, Gao, Kun
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943363/
https://ncbi.nlm.nih.gov/pubmed/31911863
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