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Tumor suppressor SPOP mediates the proteasomal degradation of progesterone receptors (PRs) in breast cancer cells

Progesterone induces proliferation of breast cancer cells and contributes to the development of breast cancer. The effects of progesterone are mediated by progesterone receptors (PRs). However, it is still not fully understood how the proliferative effects of PR is regulated in vivo. Increasing amou...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Gao, Kun, Jin, Xiaofeng, Tang, Yan, Ma, Jian, Peng, Jingtiao, Yu, Long, Zhang, Pingzhao, Wang, Chenji
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656742/
https://ncbi.nlm.nih.gov/pubmed/26693071
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