Tumor suppressor SPOP mediates the proteasomal degradation of progesterone receptors (PRs) in breast cancer cells

Progesterone induces proliferation of breast cancer cells and contributes to the development of breast cancer. The effects of progesterone are mediated by progesterone receptors (PRs). However, it is still not fully understood how the proliferative effects of PR is regulated in vivo. Increasing amou...

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Publicat a:Am J Cancer Res
Autors principals: Gao, Kun, Jin, Xiaofeng, Tang, Yan, Ma, Jian, Peng, Jingtiao, Yu, Long, Zhang, Pingzhao, Wang, Chenji
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656742/
https://ncbi.nlm.nih.gov/pubmed/26693071
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