Resumption of Autophagy by Ubisol-Q(10) in Presenilin-1 Mutated Fibroblasts and Transgenic AD Mice: Implications for Inhibition of Senescence and Neuroprotection

Alzheimer's disease (AD) is the most prevalent form of dementia and is associated with loss of memory, amyloid-beta plaque buildup, and neurofibrillary tangles. These features might be a result of neuronal cell death in the cerebral cortex and hippocampal regions of the brain. AD pathologies ca...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Vegh, Caleb, Pupulin, Simon, Wear, Darcy, Culmone, Lauren, Huggard, Rachel, Ma, Dennis, Pandey, Siyaram
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942887/
https://ncbi.nlm.nih.gov/pubmed/31934268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7404815
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