A Bird’s-Eye View of the Multiple Biochemical Mechanisms that Propel Pathology of Alzheimer’s Disease: Recent Advances and Mechanistic Perspectives on How to Halt the Disease Progression Targeting Multiple Pathways

Neurons consume the highest amount of oxygen, depend on oxidative metabolism for energy, and survive for the lifetime of an individual. Therefore, neurons are vulnerable to death caused by oxidative-stress, accumulation of damaged and dysfunctional proteins and organelles. There is an exponential in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Alzheimers Dis
Prif Awduron: Vegh, Caleb, Stokes, Kyle, Ma, Dennis, Wear, Darcy, Cohen, Jerome, Ray, Sidhartha D., Pandey, Siyaram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: IOS Press 2019
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598003/
https://ncbi.nlm.nih.gov/pubmed/31127770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-181230
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