A Bird’s-Eye View of the Multiple Biochemical Mechanisms that Propel Pathology of Alzheimer’s Disease: Recent Advances and Mechanistic Perspectives on How to Halt the Disease Progression Targeting Multiple Pathways

Neurons consume the highest amount of oxygen, depend on oxidative metabolism for energy, and survive for the lifetime of an individual. Therefore, neurons are vulnerable to death caused by oxidative-stress, accumulation of damaged and dysfunctional proteins and organelles. There is an exponential in...

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Bibliographische Detailangaben
Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Vegh, Caleb, Stokes, Kyle, Ma, Dennis, Wear, Darcy, Cohen, Jerome, Ray, Sidhartha D., Pandey, Siyaram
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2019
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598003/
https://ncbi.nlm.nih.gov/pubmed/31127770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-181230
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