A Bird’s-Eye View of the Multiple Biochemical Mechanisms that Propel Pathology of Alzheimer’s Disease: Recent Advances and Mechanistic Perspectives on How to Halt the Disease Progression Targeting Multiple Pathways

Neurons consume the highest amount of oxygen, depend on oxidative metabolism for energy, and survive for the lifetime of an individual. Therefore, neurons are vulnerable to death caused by oxidative-stress, accumulation of damaged and dysfunctional proteins and organelles. There is an exponential in...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Vegh, Caleb, Stokes, Kyle, Ma, Dennis, Wear, Darcy, Cohen, Jerome, Ray, Sidhartha D., Pandey, Siyaram
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598003/
https://ncbi.nlm.nih.gov/pubmed/31127770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-181230
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