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Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease

Mitochondria are essential organelles within the cell where most ATP is produced through oxidative phosphorylation (OXPHOS). A subset of the genes needed for this process are encoded by the mitochondrial DNA (mtDNA). One consequence of OXPHOS is the production of mitochondrial reactive oxygen specie...

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Publicat a:FEBS Lett
Autors principals: Nissanka, Nadee, Moraes, Carlos T.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942696/
https://ncbi.nlm.nih.gov/pubmed/29281123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12956
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