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Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism

BACKGROUND: The mitochondrial genome (mtDNA) is particularly susceptible to damage mediated by reactive oxygen species (ROS). Although elevated ROS production and elevated biomarkers of oxidative stress have been found in tissues from children with autism spectrum disorders, evidence for damage to m...

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Detalhes bibliográficos
Main Authors: Napoli, Eleonora, Wong, Sarah, Giulivi, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570390/
https://ncbi.nlm.nih.gov/pubmed/23347615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-4-2
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