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Role of p53, Mitochondrial DNA Deletions, and Paternal Age in Autism: A Case-Control Study
BACKGROUND: The tumor suppressor p53 responds to a variety of environmental stressors by regulating cell cycle arrest, apoptosis, senescence, DNA repair, bioenergetics and mitochondrial DNA (mtDNA) copy number maintenance. Developmental abnormalities have been reported in p53-deficient mice, and alt...
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| Publicado no: | Pediatrics |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Academy of Pediatrics
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811307/ https://ncbi.nlm.nih.gov/pubmed/27033107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1542/peds.2015-1888 |
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