Role of p53, Mitochondrial DNA Deletions, and Paternal Age in Autism: A Case-Control Study

BACKGROUND: The tumor suppressor p53 responds to a variety of environmental stressors by regulating cell cycle arrest, apoptosis, senescence, DNA repair, bioenergetics and mitochondrial DNA (mtDNA) copy number maintenance. Developmental abnormalities have been reported in p53-deficient mice, and alt...

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Bibliografiske detaljer
Udgivet i:Pediatrics
Main Authors: Wong, Sarah, Napoli, Eleonora, Krakowiak, Paula, Tassone, Flora, Hertz-Picciotto, Irva, Giulivi, Cecilia
Format: Artigo
Sprog:Inglês
Udgivet: American Academy of Pediatrics 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811307/
https://ncbi.nlm.nih.gov/pubmed/27033107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1542/peds.2015-1888
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