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A benzenesulfonamide derivative as a novel PET radioligand for CXCR4
CXCR4 is involved in various diseases such as inflammation, tumor growth, and cancer metastasis through the interaction with its natural endogenous ligand, chemokine CXCL12. In an effort to develop imaging probes for CXCR4, we developed a novel small molecule CXCR4-targeted PET agent (compound 5) by...
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| Udgivet i: | Bioorg Med Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942325/ https://ncbi.nlm.nih.gov/pubmed/31843463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.115240 |
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