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A benzenesulfonamide derivative as a novel PET radioligand for CXCR4

CXCR4 is involved in various diseases such as inflammation, tumor growth, and cancer metastasis through the interaction with its natural endogenous ligand, chemokine CXCL12. In an effort to develop imaging probes for CXCR4, we developed a novel small molecule CXCR4-targeted PET agent (compound 5) by...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Oum, Yoon Hyeun, Shetty, Dinesh, Yoon, Younghyoun, Liang, Zhongxing, Voll, Ronald J., Goodman, Mark M., Shim, Hyunsuk
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942325/
https://ncbi.nlm.nih.gov/pubmed/31843463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.115240
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