Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne

The establishment of polyubiquitin conjugates with distinct linkages play important roles in the DNA damage response. Much remains unknown about the regulation of linkage-specific ubiquitin signaling at sites of DNA damage. Here we reveal that Cezanne (also known as Otud7B) deubiquitinating enzyme p...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Wu, Xiao, Liu, Shichang, Sagum, Cari, Chen, Jianji, Singh, Rajesh, Chaturvedi, Apurva, Horton, John R., Kashyap, Tanuja R., Fushman, David, Cheng, Xiaodong, Bedford, Mark T., Wang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942045/
https://ncbi.nlm.nih.gov/pubmed/31699778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.332395.119
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