Dysregulation of RNA Splicing in Tauopathies

Pathological aggregation of RNA binding proteins (RBPs) is associated with dysregulation of RNA splicing in PS19 P301S tau transgenic mice and in Alzheimer’s disease brain tissues. The dysregulated splicing particularly affects genes involved in synaptic transmission. The effects of neuroprotective...

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Publicat a:Cell Rep
Autors principals: Apicco, Daniel J., Zhang, Cheng, Maziuk, Brandon, Jiang, Lulu, Ballance, Heather I., Boudeau, Samantha, Ung, Choong, Li, Hu, Wolozin, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941411/
https://ncbi.nlm.nih.gov/pubmed/31875547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.093
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