Dysregulation of RNA Splicing in Tauopathies

Pathological aggregation of RNA binding proteins (RBPs) is associated with dysregulation of RNA splicing in PS19 P301S tau transgenic mice and in Alzheimer’s disease brain tissues. The dysregulated splicing particularly affects genes involved in synaptic transmission. The effects of neuroprotective...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Apicco, Daniel J., Zhang, Cheng, Maziuk, Brandon, Jiang, Lulu, Ballance, Heather I., Boudeau, Samantha, Ung, Choong, Li, Hu, Wolozin, Benjamin
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941411/
https://ncbi.nlm.nih.gov/pubmed/31875547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.093
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