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Hyperglycemia-induced cardiomyocyte death is mediated by lysosomal membrane injury and aberrant expression of Cathepsin D
Hyperglycemia is an independent risk factor for diabetic heart failure. However, the mechanisms that mediate hyperglycemia-induced cardiac damage remain poorly understood. Previous studies have shown an association between lysosomal dysfunction and diabetic heart injury. The present study examined i...
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| Pubblicato in: | Biochem Biophys Res Commun |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941191/ https://ncbi.nlm.nih.gov/pubmed/31862139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.12.051 |
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