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Aldh2 Attenuates Stem Cell Factor/Kit-Dependent Signaling and Activation in Mast Cells

Mitochondrial aldehyde dehydrogenase (ALDH2) metabolizes endogenous and exogenous aldehydes and protects cells against oxidative injury. Inactivating genetic polymorphisms in humans are common and associate with alcohol flush reactions. However, whether mast cell Aldh2 activity impacts normal mast c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Do-Kyun, Cho, Young-Eun, Song, Byoung-Joon, Kawamoto, Toshihiro, Metcalfe, Dean D., Olivera, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940998/
https://ncbi.nlm.nih.gov/pubmed/31835486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246216
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