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Interaction of DJ-1 with Lyn is essential for IgE-mediated stimulation of human mast cells

BACKGROUND: DJ-1 is a redox-sensitive protein with multiple roles in cell homeostasis whose levels are altered in mast cell (MC)-related disorders. However, whether DJ-1 can regulate human MC function is unknown. OBJECTIVE: We sought to investigate the potential role of DJ-1 in the responses of huma...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Kim, Do-Kyun, Beaven, Michael A., Metcalfe, Dean D., Olivera, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899056/
https://ncbi.nlm.nih.gov/pubmed/29031599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.08.030
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