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Optimizing Manufacturing Protocols of Chimeric Antigen Receptor T Cells for Improved Anticancer Immunotherapy

Chimeric antigen receptor (CAR) T cell therapy can achieve outstanding response rates in heavily pretreated patients with hematological malignancies. However, relapses occur and they limit the efficacy of this promising treatment approach. The cellular composition and immunophenotype of the administ...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Stock, Sophia, Schmitt, Michael, Sellner, Leopold
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940894/
https://ncbi.nlm.nih.gov/pubmed/31835562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246223
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