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Optimizing Manufacturing Protocols of Chimeric Antigen Receptor T Cells for Improved Anticancer Immunotherapy

Chimeric antigen receptor (CAR) T cell therapy can achieve outstanding response rates in heavily pretreated patients with hematological malignancies. However, relapses occur and they limit the efficacy of this promising treatment approach. The cellular composition and immunophenotype of the administ...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Stock, Sophia, Schmitt, Michael, Sellner, Leopold
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940894/
https://ncbi.nlm.nih.gov/pubmed/31835562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246223
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